Reading Epigenetic Age Clocks with Appropriate Skepticism

Epigenetic clocks have moved from research settings into consumer products. Their interpretation, however, remains an unsettled science.

Key findings

• Effect sizes vary substantially across studies.
• Applicability to healthy adults remains contingent on further evidence.
• Careful monitoring is warranted when interventions are used off-label.

Clinical context

Recommendations should always be considered within the individual patient's clinical picture.

Limitations

Publication bias, heterogeneous protocols, and short follow-up limit strong conclusions.

References

1. Author et al. Journal Placeholder. Year. Volume, Pages.
2. Author et al. Journal Placeholder. Year. Volume, Pages.